The event will take place on wednesday, April 6th 2022 at 1:00 pm, Amphitheater Leon Hirsch, IRCAD Strasbourg (1 Place de l'Hopital).
Abstract
Despite the massive deployment of imaging technologies in the operating rooms, the ability of surgeons to distinguish healthy from diseased tissues remains limited to the assessment of tissues status based on subjective inputs. The lack of tools for intraoperative tissue status assessment has been the main source of motivation for this doctoral project. To address this need, a clinically-compatible imaging platform has been developed for oxygenation and fluorescence imaging in real-time. The capability of the platform to detect and quantify ischemia has been demonstrated through preclinical trials, by comparison with standard of care methods. A field of application is blood perfusion assessment for reconstructive procedures in the context of colorectal cancer surgery. The multimodal nature of the developed imaging device has been exploited by combining endogenous imaging of optical properties with exogenous fluorescence imaging, in the context of oncologic surgery using targeted agents. A fluorescence quantification technique was thus validated in preclinical trials.
Jury members
- Prof Sylvain Gioux, Intuitive Surgical SARL - supervisor
- Prof Sylvain Lecler, INSA Strasbourg - co-supervisor
- Prof Walter Blondel, CRAN, Université de Lorraine - reviewer
- Prof Éric Vibert, Hôpital Paul Brousse, Centre Hépato-Biliaire - reviewer
- Dr. Alexander Vahrmeijer, Leiden University Medical Center - examiner
- Dr. Michele Diana, IRCAD France - examiner