The event will take place on November 20, 2024 in the thesis room at the Faculty of Medicine at the University of Strasbourg.
Abstract
The objective of this thesis is to develop a new full-field optical coherence tomography (FF-OCT) system for imaging biological tissues in-vivo. This experimental system combines full-field optical coherence tomography (FF-OCT) with an off-axis interferometry technique. With this method, it is possible to simultaneously obtain amplitude and phase images from a single interferogram acquisition. The amplitude images allow for tomographic imaging of biological tissues in vivo with micrometer-level resolution, demonstrating the system’s capability to capture images in in-vivo scenarios.
Direct access to phase images also offers the possibility to incorporate additional contrast modalities, such as elastography. During this thesis, elastography was integrated into the experimental system, enabling the acquisition of stiffness maps of samples. This approach was successfully validated on agarose samples, which mimic the mechanical properties of biological tissues.
Jury Members
- Reviewer: Prof. Arnaud Dubois, Université Paris-Saclay, Charles Fabry Laboratory
- • Reviewer: Prof. Gilles Tessier, Sorbonne University, Vision Institute
- • Examiner: Dr. Serge Miemon, ONERA - Paris Eye Imaging
- • Supervisor: Prof. Nadia Bahlouli, Université de Strasbourg, ICube
- • Co-supervisor: Prof. Sybille Facca, Université de Strasbourg, ICube, University Hospitals of Strasbourg, Hand Surgery Department
- • Advisor: Dr. Amir Na
